Maternal Hyperglycemia

Maternal Hyperglycemia

• Causes fetal hyperglycemia
• Leading to fetal hyperinsulinaemia
• Fetal hyperinsulinaemia - even short periods (1-2hours) lead to detrimental consequences in:
  • fetal growth
  • fetal well-being
• Fetal Hyperinsulinaemia
• Promotes storage of excess nutrients - macrosomnia
• Increased catabolism of excess nutrients - energy usage and ¯ fetal oxygen storage
• Episodic fetal hypoxia­ catecholamines causing:               - hypertension,

                                - cardiac remodelling and hypertrophy,

                                 ­ Erythropoietin, RBC’s, haematocrit causing

                                    poor circulation and hyperbilirubinaemia

Pregnancy Complications in Diabetes Maternal

 Preterm labor

Infectious morbidities

Hydramnios

Hypertensive disorders and nephropathy

Worsening of diabetic retinopathy